Wealthy big game hunter Tom Newcliffe (Calvin Lockhart) has tracked and killed practically every type of animal in the world. But one creature still evades him, the biggest game of all - a werewolf. Tom invites five guests -- Dr. Christopher Lundgren (Peter Cushing), Paul Foote (Tom Chadbon), Bennington (Charles Gray), Jan Jarmokowski (Michael Gambon) and Davina (Ciaran Madden) -- to his island knowing they all are tied one way or another to unusual circumstances of death - and that one of them is a werewolf. Add to the mix Tom's alluring wife Caroline (Marlene Clark) and surveillance expert, Pavel (Anton Diffring), Tom tracks the werewolf but is unable to kill it. One by one the creature kills the isolated guests.