Jack (Jared Leto) is a Gen-Exer with nowhere to go until he gets caught in bed with the wrong woman. Now, with three thugs after him, he and best pal Pilot (Jake Gyllenhaal) hit the road to Seattle. Along the way, they encounter sexy Cassie (Selma Blair), who decides to hitch a ride. Together, they end up on the wildest trip of their lives!
