The F&B ambulance company, is the home away from home for a motley crew of drivers obsessed with bringing in more patients than their competition while working their respective shifts. Bill Cosby stars as Mother, the wisecracking leader who plays by his own rules and drives with his loyal partner, Leroy (Bruce Davison). Together, Mother and Leroy encounter a wide variety of adventures as they race around town looking for calamity and disaster. Jugs (Raquel Welch) is the aptly nicknamed buxom secretary who consistently dismisses the advances of the lewd and crude drivers while secretly studying to become the first female driver at F&B--until she meets Speed (Harvey Keitel), an ex-cop and Vietnam vet under investigation for drug charges who joins the F&B crew. As the company teeters near bankruptcy and disaster strikes, the drivers must band together to keep their struggling company afloat.