Eccentric author Mort Rainey (Johnny Depp) finds his life spiraling out of control. With a drinking problem and a cigarette habit he can't shake, Mort can barely function when his wife (Maria Bello) leaves him and he abandons his work. In the midst of his anguish, a deranged man, John Shooter, (John Turturro) appears at Mort's New York cabin, claiming that Mort has plagiarized one of his stories. As his wife pushes Mort to finalize their divorce and Shooter systematically destroys his life, he struggles to restore order to an increasingly insane situation.