A young, beautiful woman named Carol (Olinka Berova) is plagued by hallucinatory voices calling her "Ayesha" and is drawn by a mysterious force toward the east. During her voyage, she meets Dr Philip Smith (Edward Judd) who decides to accompany Carol to her unknown destination.
Eventually, the tow reach the lost city of Kuma where Carol is greeted as the reincarnation of Queen Ayesha, the beloved of King Killikrates (John Richardson). Philip is imprisoned and meets Za-Tor (Noel Willman) who tells him of the high priest's deceitful plan to obtain the secret of immortality by bringing back Ayesha to King Killikrates. Will Philip escape in time to reveal the truth and save Carol from destruction?
