A Fantastic and spectacular voyage... Through the human body... Into the brain.

Shrunk to microscopic size, an elite scientific and medical team enters the bloodstream of an ailing scientist in a desperate effort to save his life. Battling the body's incredible defenses, the crew must complete their mission before time runs out.

The film was to win Oscars for Best Visual Effects (by Art Cruikschank) and Art Direction. The legacy of the film was to continue, as Fantastic Voyage later received an animated spin-off show.