Having survived a vigilante slaughter, four hard-luck strangers - gambler Stubby Preston (Fabio Testi), a pregnant prostitute (Lynne Frederick), the town drunk (Michael J. Pollard) and a madman who sees dead people (Harry Baird) - escape into the lawless frontier. But when they meet a sadistic bandit named Chaco (Tomas Milian), the four are plunged into a nightmare of torture, brutality and beyond. In a land that screams with the pain of the damned, can four lost souls find redemption and revenge?

Due to its graphic violence, Four of the Apocalypse was banned or censored in many countries and never seen in America. Meanwhile, fans - and Lucio Fulci himself - considered it to be one of the greatest films of the maestro's career.