David Lynch's first film since the award-winning Mulholland Drive (and his first shot completely on digital) is a complex Hollywood mystery that blurs the lines between fantasy and reality and features an astonishing performance by Laura Dern.

Dern plays Nikki Grace, an actress preparing for her biggest role yet, a Hollywood movie from an acclaimed director (played by Jeremy Irons) opposite an amorous leading man (Justin Theroux). But when she finds herself falling for her co-star, she realizes that her life is beginning to mimic the fictional film that they're shooting. Adding to her confusion is the revelation that the current film is a remake of a doomed polish production that was never finished due to an unspeakable tragedy...