Last year, Tony Soprano cheated death when he was shot by his now institutionalized Uncle Junior. While Tony continues to muse about his second chance at life, he faces a myriad of immediate, stress-inducing crises at home, at work and from the law. Tony's wife Carmela plans for a future she's not sure will arrive, and son AJ and daughter Meadow find that adulthood holds its own surprises. Meanwhile, at work, Tony comes to doubt the allegiances of many of those closest to him? No one, not Paulie, Bobby, Silvio or even Christopher is above suspicion.

The clock is ticking. Time is running out. But on who?