Mrs Palfrey at The Claremont is a comedy drama based on the best selling novel by the late, celebrated English author, Elizabeth Taylor.

The story centers around an elegant elderly lady (Mrs Palfrey) who, after being recently widowed, moves from Scotland to London to be near to her 26 year old grandson, Desmond. When Desmond fails to return any of her several phone calls, or visit her at the resident hotel she is staying (The Claremont), fate brings her together with a young writer, Ludovic Meyer, after she has an accident outside his basement flat.

Eventually, Ludo ends up helping Mrs. Palfrey by playing a charade - pretending to be her grandson, so that the other off-beat elderly residents of the hotel believe that she hasn't been lying, and that she really does have a grandson.

The two newly found friends discover they have a lot more in common with each other then they do with other people their own age. Thus begins a deep-rooted friendship that is far reaching, and everlasting.