The explosive, action-packed adventure in one of the all-time most popular superhero sagas unfolds with a cure in reach for the world's most primal force of fury: The Incredible Hulk. We find scientist Bruce Banner (Edward Norton) living in shadows, scouring the planet for an antidote. But the warmongers who dream of abusing his powers won't leave him alone, nor will his need to be with the only woman he has ever loved, Betty Ross (Liv Tyler).

Upon returning to civilization, our brilliant doctor is ruthlessly pursued by The Abomination - a nightmarish beast of pure adrenaline and aggression whose powers match The Hulk's own. A fight of comic-book proportions ensues as Banner must call upon the hero within to rescue New York City from total destruction...