Based on Vivienne Laxdal's witty play, These Girls updates the classic sex farce genre for the twenty-first century.

Set in small-town New Brunswick, the film focuses on Keira (Caroline Dhavernas) and her two best friends: the ultra-conventional, pink-obsessed Glory (Amanda Walsh), and Seventh Day Adventist, Lisa (Holly Lewis). With the exception of Lisa (who's destined for a religious college), their futures are pretty much up in the air. Keira in particular has no idea what she wants to do and is especially annoyed with her father's constant pestering about university. Her disinterest in the local boys her age who are proud to be going nowhere quickly changes when an alternative presents itself in the form of hunky local tough-guy Keith Clark (David Boreanaz). When the girls learn that Keith is growing marijuana in his back yard, Keira and Lisa sneak in to steal some, only to find babysitter Glory and Keith (who's slightly older and quite married) together in bed. Envious, both Keira and Lisa become determined to sleep with Keith, and all three start to blackmail him into sex.